Gene-environment interaction in molar-incisor hypomineralization

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Molar incisor hypomineralization: An update

Molar incisor hypomineralization (MIH) is a congenital disease which is increasing in prevalence. It affects permanent first molars and, often to a lesser degree, permanent incisors with variable severity. The etiology is unknown, but various risk factors have been put forward. Differential diagnosis is mandatory not to confound MIH with other diseases such as amelogenesis imperfecta or fluoros...

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Molar Incisor Hypomineralization, Prevalence, and Etiology

Aim. To evaluate the prevalence and possible etiological factors associated with molar incisor hypomineralization (MIH) among a group of children in Jeddah, Saudi Arabia. Methods. A group of 8-12-year-old children were recruited (n = 267) from the Pediatric Dental Clinics at the Faculty of Dentistry, King Abdulaziz University. Children had at least one first permanent molar (FPM), erupted or pa...

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On the Etiology of Molar-Incisor Hypomineralization.

Molar-incisor hypomineralization (MIH) is a condition that is defined based on its peculiar clinical presentation. Reports on the etiology of the condition and possible risk factors are inconclusive and the original suggestion that MIH is an idiopathic condition is often cited. Our group was the first to suggest MIH has a genetic component that involves genetic variation in genes expressed duri...

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Definition and scoring system of molar incisor hypomineralization: A review

Objectives: A definition and classification system for molar incisor hypomineralization (MIH) was first suggested by the European Academy of Pediatric Dentistry (EAPD) in 2003. Since then, there has been growing interest in these mineralization defects due to esthetic and cariogenic susceptibility concerns. The aim of this review was to evaluate studies on MIH in an attempt to provide evidence ...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2021

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0241898